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Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, and it blocks HCN1 receptors. However, at higher doses it may also bind to the opioid mu and sigma receptors.
Buy Ketamine Powder
Buy Ketamine Powder from the most reputable vendor of all Ketamine products discreetly and safely. Ketamine (hydrochloride) is a general anesthetic manufactured by Parke Davis and marketed under the name “ketolar.”
Several smaller pharmaceutical firms also distribute it. Ketamine from Parke Davis is presented in a sealed multipurpose container of 50 mg content in general. It is also used as a veterinary anesthetic and is sold on the black market in powdered form.
This drug is used clinically as a general anesthetic. It is considered a mild drug and is often given to children and the elderly. Its characteristics were discovered after many recipients reported what they felt upon coming out of anesthesia. The remaining experiments showed that a dose much lower than the anesthetic produces a great intensity
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Pharmacology of Ketamine powder
Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, and it blocks HCN1 receptors. However, at higher doses it may also bind to the opioid mu and sigma receptors. It disrupts the neurotransmitter (brain chemical) glutamate. Glutamate is involved with learning, memory, emotion, and pain recognition. It can exhibit sympathomimetic activity which can lead to rapid heart rate and elevated blood pressure.
It is related to phencyclidine (PCP), but has less than 10% of the potency of pure PCP.
This agent is a lipid-soluble compound, and has an initial rapid distribution and a large volume of distribution, with a half-life of 10 to 15 minutes. Secondarily, the drug distributes into peripheral tissues with a slower elimination half-life of up to 3 hours, undergoes hepatic metabolism and is excreted in the urine.
How Quickly Does Ketamine Work?
- An injection yields a quick response, with effects occurring in seconds to minutes.
- “Snorting” leads to effects in roughly 5 to 15 minutes (this is the most common method of abuse).
- Oral consumption requires between 5 and 30 minutes.
The effects of abuse typically last 1 to 2 hours, but the user’s judgment, senses, and coordination may be affected for up to 24 hours or longer. Sensations the user may seek include floating, stimulation, and visual effects.
High doses may dangerously reduce breathing, and lead to muscle spasms or weakness, dizziness, balance difficulty, impaired vision, slurred speech, nausea and vomiting, and severe confusion.
Binge use, where the user indulges in the drug in excess amounts in a short period has been reported, as well.,
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